A biofilm microenvironment-responsive one-for-all bactericidal nanoplatform for photothermal-augmented multimodal synergistic therapy of pathogenic bacterial biofilm infection

We rationally construct a biofilm microenvironment-responsive bactericidal nanoplatform (ZnPMp) consisting of ZnO core, a Fe 3+ -doped polydopamine coating and methylene blue (MB) payload for combined CT/CDT/PTT/PDT multi-mode antibacterial therapy.