亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

Machine learning as an adjunct to expert observation in classification of radiographic knee osteoarthritis: findings from the Hertfordshire Cohort Study

沃马克 骨关节炎 医学 队列 接收机工作特性 物理疗法 判别式 射线照相术 内科学 外科 机器学习 病理 计算机科学 替代医学
作者
Leo D. Westbury,Nicholas R. Fuggle,Diogo Pereira,Hiroyuki Oka,Noriko Yoshimura,Noriyuki Oe,Sasan Mahmoodi,Mahesan Niranjan,Elaine Dennison,Cyrus Cooper
出处
期刊:Aging Clinical and Experimental Research [Springer Science+Business Media]
卷期号:35 (7): 1449-1457 被引量:3
标识
DOI:10.1007/s40520-023-02428-5
摘要

Abstract Background Osteoarthritis is the most prevalent type of arthritis. Many approaches exist for characterising radiographic knee OA, including machine learning (ML). Aims To examine Kellgren and Lawrence (K&L) scores from ML and expert observation, minimum joint space and osteophyte in relation to pain and function. Methods Participants from the Hertfordshire Cohort Study, comprising individuals born in Hertfordshire from 1931 to 1939, were analysed. Radiographs were assessed by clinicians and ML (convolutional neural networks) for K&L scoring. Medial minimum joint space and osteophyte area were ascertained using the knee OA computer-aided diagnosis (KOACAD) program. The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) was administered. Receiver operating characteristic analysis was implemented for minimum joint space, osteophyte, and observer- and ML-derived K&L scores in relation to pain (WOMAC pain score > 0) and impaired function (WOMAC function score > 0). Results 359 participants (aged 71–80) were analysed. Among both sexes, discriminative capacity regarding pain and function was fairly high for observer-derived K&L scores [area under curve (AUC): 0.65 (95% CI 0.57, 0.72) to 0.70 (0.63, 0.77)]; results were similar among women for ML-derived K&L scores. Discriminative capacity was moderate among men for minimum joint space in relation to pain [0.60 (0.51, 0.67)] and function [0.62 (0.54, 0.69)]. AUC < 0.60 for other sex-specific associations. Discussion Observer-derived K&L scores had higher discriminative capacity regarding pain and function compared to minimum joint space and osteophyte. Among women, discriminative capacity was similar for observer- and ML-derived K&L scores. Conclusion ML as an adjunct to expert observation for K&L scoring may be beneficial due to the efficiency and objectivity of ML.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
小小完成签到 ,获得积分10
4秒前
mama完成签到 ,获得积分10
24秒前
量子星尘发布了新的文献求助10
26秒前
29秒前
Lucas应助科研通管家采纳,获得30
43秒前
充电宝应助科研通管家采纳,获得10
43秒前
大模型应助科研通管家采纳,获得10
43秒前
科研通AI2S应助科研通管家采纳,获得10
43秒前
思源应助科研通管家采纳,获得10
43秒前
共享精神应助君君采纳,获得10
52秒前
1分钟前
1分钟前
1分钟前
1分钟前
1分钟前
Bluestar发布了新的文献求助30
1分钟前
1分钟前
量子星尘发布了新的文献求助10
1分钟前
慕青应助oscar采纳,获得10
1分钟前
2分钟前
mashibeo完成签到,获得积分10
2分钟前
CipherSage应助科研通管家采纳,获得10
2分钟前
2分钟前
量子星尘发布了新的文献求助10
3分钟前
3分钟前
Wu发布了新的文献求助10
3分钟前
香蕉觅云应助Wu采纳,获得10
3分钟前
3分钟前
mzf发布了新的文献求助10
3分钟前
3分钟前
3分钟前
Bluestar完成签到,获得积分10
3分钟前
魏建威发布了新的文献求助10
3分钟前
大个应助huang采纳,获得10
3分钟前
魏建威完成签到,获得积分20
3分钟前
3分钟前
3分钟前
oscar发布了新的文献求助10
4分钟前
4分钟前
huang发布了新的文献求助10
4分钟前
高分求助中
Picture Books with Same-sex Parented Families: Unintentional Censorship 1000
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 310
宽量程高线性度柔性压力传感器的逆向设计 300
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3980909
求助须知:如何正确求助?哪些是违规求助? 3524650
关于积分的说明 11222394
捐赠科研通 3262165
什么是DOI,文献DOI怎么找? 1801114
邀请新用户注册赠送积分活动 879595
科研通“疑难数据库(出版商)”最低求助积分说明 807431