转录因子
细胞生物学
基因
生物
磷酸化
激酶
耐寒性
水稻
遗传学
植物
作者
Liang Xu,Lijia Yang,Aipeng Li,Jiazhuo Guo,Huanyu Wang,Haoyue Qi,Ming Li,Pingfang Yang,Shiyong Song
出处
期刊:Science Advances
[American Association for the Advancement of Science (AAAS)]
日期:2024-08-30
卷期号:10 (35)
标识
DOI:10.1126/sciadv.ado4788
摘要
Cold stress, a prominent adverse environmental factor, severely hinders rice growth and productivity. Unraveling the complex mechanisms governing chilling tolerance in rice is crucial for molecular breeding of cold-tolerant varieties. Here, we identify an APETALA2/Ethylene Responsive Factor (AP2/ERF) transcription factor, OsERF52, as a positive modulator in response to low temperatures. OsERF52 directly regulates the expression of C-Repeat Binding Factor ( CBF ) genes in rice. In addition, Osmotic Stress/ABA-Activated Protein Kinase 9–mediated phosphorylation of OsERF52 at S261 enhances its stability and interaction with Ideal Plant Architecture 1 and OsbHLH002/OsICE1. This collaborative activation leads to the expression of OsCBFs , thereby initiating the chilling response in rice. Notably, plants with base-edited OsERF52 S261D -3HA exhibit enhanced chilling resistance without yield penalty. Our findings unveil the mechanism orchestrated by a regulatory framework involving a protein kinase and transcription factors from diverse families, offering potential genetic resources for developing chilling-tolerant rice varieties.
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