彭布罗利珠单抗
医学
化疗
奥拉帕尼
肿瘤科
内科学
肺癌
癌症
免疫疗法
聚合酶
聚ADP核糖聚合酶
生物化学
化学
基因
作者
Maximilian J. Hochmair,Michael Schenker,Manuel Cobo,Tae Min Kim,Özgür Özyılkan,Maria Smagina,Leonova Viktoriya,Terufumi Kato,А. А. Феденко,Flávia De Angelis,Achim Rittmeyer,Jhanelle E. Gray,Alastair Greystoke,Himani Aggarwal,Qinlei Huang,Bin Zhao,Humberto Lara-Guerra,Ernest Nadal
标识
DOI：10.1016/j.jtho.2024.10.012
摘要
PARP inhibitors can upregulate PD-L1 expression and promote immune-mediated responses, and may improve efficacy of first-line anti‒PD-1‒based therapies in patients with metastatic squamous NSCLC.
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