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HomeRadiologyVol. 312, No. 2 PreviousNext Reviews and CommentaryEditorialMedium Vessel Occlusions: The Next Frontier in Endovascular Thrombectomy for Acute Ischemic StrokeJoan C. Wojak Joan C. Wojak Author AffiliationsFrom the Department of Radiology, Our Lady of Lourdes Regional Medical Center, 4801 Ambassador Caffery Pkwy, Lafayette, LA 70508.Address correspondence to the author (email: [email protected]).Joan C. Wojak Published Online:Aug 6 2024https://doi.org/10.1148/radiol.241565See also the article by the MAD-MT Consortium in this issue.MoreSectionsFull textPDF ToolsAdd to favoritesCiteTrack CitationsPermissionsReprints ShareShare onFacebookXLinked In References1. National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med 1995;333(24):1581–1587. MedlineGoogle Scholar2. Lewandowski CA, Frankel M, Tomsick TA, et al. Combined intravenous and intra-arterial r-TPA versus intra-arterial therapy of acute ischemic stroke: Emergency Management of Stroke (EMS) Bridging Trial. Stroke 1999;30(12):2598–2605. MedlineGoogle Scholar3. Gobin YP, Starkman S, Duckwiler GR, et al. MERCI 1: a phase 1 study of Mechanical Embolus Removal in Cerebral Ischemia. Stroke 2004;35(12):2848–2854. MedlineGoogle Scholar4. Berkhemer OA, Fransen PSS, Beumer D, et al; MR CLEAN Investigators. A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med 2015;372(1):11–20. MedlineGoogle Scholar5. Campbell BCV, Mitchell PJ, Kleinig TJ, et al; EXTEND-IA Investigators. Endovascular therapy for ischemic stroke with perfusion-imaging selection. N Engl J Med 2015;372(11):1009–1018. MedlineGoogle Scholar6. Goyal M, Demchuk AM, Menon BK, et al; ESCAPE Trial Investigators. Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med 2015;372(11):1019–1030. MedlineGoogle Scholar7. Saver JL, Goyal M, Bonafe A, et al; SWIFT PRIME Investigators. Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. N Engl J Med 2015;372(24):2285–2295. MedlineGoogle Scholar8. Dmytriw AA, Ghozy S, Salim H, et al; The MAD-MT Consortium. Assessment of Thrombectomy versus Combined Thrombolysis and Thrombectomy in patients with acute ischemic stroke and medium vessel occlusion. Radiology 2024;301(2):e233041. Google Scholar9. Wang Y, Cai X, Fang Q, Zhu J. Efficacy and safety outcomes of Tenecteplase versus Alteplase for thrombolysis of acute ischemic stroke: A meta-analysis of 9 randomized controlled trials. J Neurol Sci 2024;458:122912. MedlineGoogle ScholarArticle HistoryReceived: May 29 2024Revision requested: July 1 2024Revision received: July 2 2024Accepted: July 9 2024Published online: Aug 06 2024 FiguresReferencesRelatedDetailsAccompanying This ArticleAssessment of Thrombectomy versus Combined Thrombolysis and Thrombectomy in Patients with Acute Ischemic Stroke and Medium Vessel OcclusionAug 6 2024RadiologyRecommended Articles Multiphase MR Angiography Collateral Map: Functional Outcome after Acute Anterior Circulation Ischemic StrokeRadiology2020Volume: 295Issue: 1pp. 192-201Endovascular Thrombectomy Outcomes with and without Intravenous Thrombolysis for Large Ischemic Cores Identified with CT or MRIRadiology2023Volume: 309Issue: 1Mechanical Thrombectomy in Subtypes of Basilar Artery Occlusion: Relationship to Recanalization Rate and Clinical OutcomeRadiology2019Volume: 291Issue: 3pp. 730-737CT Hyperdense Artery Sign and the Effect of Alteplase in Endovascular Thrombectomy after Acute StrokeRadiology2022Volume: 305Issue: 2pp. 410-418Endovascular Thrombectomy after Large-Vessel Ischemic Stroke: Utilization, Outcomes, and Readmissions across the United StatesRadiology2021Volume: 299Issue: 1pp. 179-189See More RSNA Education Exhibits A Primer On Medium Vessel Occlusion StrokeDigital Posters2021Use of 3D Printed Neurovascular Phantoms for Evaluation and Training of Mechanical ThrombectomyDigital Posters2020Recanalization Therapy is a Matter of MismatchDigital Posters2022 RSNA Case Collection Acute ischemic strokeRSNA Case Collection2020Iatrogenic Middle Cerebral Artery PseudoaneurysmRSNA Case Collection2021Basilar Artery EntrapmentRSNA Case Collection2021 Vol. 312, No. 2 Metrics Altmetric Score PDF download