Developmental Trajectories of Brain Volume Abnormalities in Children and Adolescents With Attention-Deficit/Hyperactivity Disorder

TTENTION-DEFICIT/HYPERactivity disorder (ADHD), the most common childhood psychiatric disorder, is thought to reflect subtle abnormalities in central nervous system functioning. 1For this reason, ADHD is being studied increasingly with a variety of brain imaging techniques throughout the life span.Magnetic resonance imaging (MRI) is particularly suitable for the study of pediatric patients, providing high-resolution images without ionizing radiation.Previous MRI neuroimaging studies, most with small samples, have reported smaller anatomic areas and/or volumes in patients with ADHD in regions of the cor-