Size Does Matter: Donor Renal Volume Predicts Recipient Function Following Live Donor Renal Transplantation

No AccessJournal of UrologyAdult Urology1 Feb 2011Size Does Matter: Donor Renal Volume Predicts Recipient Function Following Live Donor Renal Transplantation Cory M. Hugen, Anthony J. Polcari, Ahmer V. Farooq, Mary P. Fitzgerald, David R. Holt, and John E. Milner Cory M. HugenCory M. Hugen Department of Urology, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois , Anthony J. PolcariAnthony J. Polcari Department of Urology, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois , Ahmer V. FarooqAhmer V. Farooq Department of Urology, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois , Mary P. FitzgeraldMary P. Fitzgerald Department of Urology, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois , David R. HoltDavid R. Holt Department of Surgery, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois , and John E. MilnerJohn E. Milner Department of Urology, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois View All Author Informationhttps://doi.org/10.1016/j.juro.2010.09.098AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: With the now routine use of computerized tomography angiography with 3-dimensional reconstruction in the donor evaluation, renal volume can be easily determined using volume calculating software. We evaluated whether donor renal volume could predict recipient renal function. Materials and Methods: Clinical data of all donor and recipient pairs undergoing live donor kidney transplantation at our institution between January 2006 and October 2009 were reviewed. The volume of the kidney selected for transplant was determined using volume calculating software, and correlated to transplant recipient nadir and 1-year serum creatinine. Multivariate regression analysis was performed to adjust for demographic and clinical variables. Results: During the study period 114 patients underwent live donor renal transplantation. Recipient nadir and 1-year serum creatinine levels were significantly correlated with the volume of donated kidney even after adjusting for age, body mass index, body surface area and donor creatinine clearance. Kidney volume also retained significance after excluding recipients from analysis who experienced acute rejection episodes. Conclusions: Larger kidney volumes calculated using 3-dimensional computerized tomography with volume calculating software are correlated with lower recipient nadir and 1-year serum creatinine levels. References 1 Organ Procurement and Transplantation Network and the Scientific Registry of Transplant Recipients: National Data US: Transplants Performed: January 1, 1988 - January 31, 2010. 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Link, Google Scholar © 2011 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byGoh Y, Wu M, Tai B, Lee K, Raman L, Teo B, Vathsala A and Tiong H (2018) Comparison of Creatinine Based and Kidney Volume Based Methods of Estimating Glomerular Filtration Rates in Potential Living Kidney DonorsJournal of Urology, VOL. 190, NO. 5, (1820-1826), Online publication date: 1-Nov-2013.Gong I, Hwang J, Choi D, Lee S, Hong Y, Hong J, Park D and Jeon H (2018) Relationship Among Total Kidney Volume, Renal Function and AgeJournal of Urology, VOL. 187, NO. 1, (344-349), Online publication date: 1-Jan-2012. Volume 185Issue 2February 2011Page: 605-609 Advertisement Copyright & Permissions© 2011 by American Urological Association Education and Research, Inc.Keywordsx-ray computedtomographykidney transplantationAcknowledgmentsRaymond Metoyer, Isabel Seraphin and Fran Wilsak provided assistance.MetricsAuthor Information Cory M. Hugen Department of Urology, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois More articles by this author Anthony J. Polcari Department of Urology, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois More articles by this author Ahmer V. Farooq Department of Urology, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois More articles by this author Mary P. Fitzgerald Department of Urology, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois Financial interest and/or other relationship with Ferring and Astellas. More articles by this author David R. Holt Department of Surgery, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois More articles by this author John E. Milner Department of Urology, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois More articles by this author Expand All Advertisement PDF downloadLoading ...