Size Effect on Cell Uptake in Well‐Suspended, Uniform Mesoporous Silica Nanoparticles

SmallVolume 5, Issue 12 p. 1408-1413 Communication Size Effect on Cell Uptake in Well-Suspended, Uniform Mesoporous Silica Nanoparticles† Fang Lu, Fang Lu Department of Chemistry and Center for Condensed Matter Sciences National Taiwan University Taipei 106 (Taiwan)Search for more papers by this authorSi-Han Wu, Si-Han Wu Department of Chemistry and Center for Condensed Matter Sciences National Taiwan University Taipei 106 (Taiwan)Search for more papers by this authorYann Hung, Yann Hung Department of Chemistry and Center for Condensed Matter Sciences National Taiwan University Taipei 106 (Taiwan)Search for more papers by this authorChung-Yuan Mou, Corresponding Author Chung-Yuan Mou cymou@ntu.edu.tw Department of Chemistry and Center for Condensed Matter Sciences National Taiwan University Taipei 106 (Taiwan)Department of Chemistry and Center for Condensed Matter Sciences National Taiwan University Taipei 106 (Taiwan).Search for more papers by this author Fang Lu, Fang Lu Department of Chemistry and Center for Condensed Matter Sciences National Taiwan University Taipei 106 (Taiwan)Search for more papers by this authorSi-Han Wu, Si-Han Wu Department of Chemistry and Center for Condensed Matter Sciences National Taiwan University Taipei 106 (Taiwan)Search for more papers by this authorYann Hung, Yann Hung Department of Chemistry and Center for Condensed Matter Sciences National Taiwan University Taipei 106 (Taiwan)Search for more papers by this authorChung-Yuan Mou, Corresponding Author Chung-Yuan Mou cymou@ntu.edu.tw Department of Chemistry and Center for Condensed Matter Sciences National Taiwan University Taipei 106 (Taiwan)Department of Chemistry and Center for Condensed Matter Sciences National Taiwan University Taipei 106 (Taiwan).Search for more papers by this author First published: 08 June 2009 https://doi.org/10.1002/smll.200900005Citations: 768 † This research was supported by a grant from the National Research Council, Taiwan (NSC-95-2752-M-002-004-PAE). Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract The size of it: Mesoporous silica nanoparticles (MSNs) of controlled size in the range 30 to 280 nm are obtained by adjusting the pH of the reaction solution. The uptake of fluorescein-labeled MSNs (green, see image) by HeLa cells is size-dependent, with maximum uptake at a nanoparticle size of 50 nm. Citing Literature Supporting Information Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Filename Description smll_200900005_sm_suppdata.pdf942.6 KB suppdata Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article. Volume5, Issue12June 19, 2009Pages 1408-1413 RelatedInformation