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Impact of Intensive Care Management on the Prognosis of Tetanus

医学 破伤风 重症监护医学 重症监护 接种疫苗 病毒学
作者
Máximo H. Trujillo,Alfredo Hinestrosa Díaz del Castillo,Jesús Beltrán España,Augusto Manzo,Rito Zerpa
出处
期刊:Chest [Elsevier BV]
卷期号:92 (1): 63-65 被引量:142
标识
DOI:10.1378/chest.92.1.63
摘要

These studies show the results of intensive care management of 306 consecutive patients with tetanus compared with 335 patients treated conservatively in the same hospital before the institution of the ICU. The impact of the ICU treatment was manifested in a decrease in mortality, from 43.58 percent to 15 percent. In addition, while patients treated conservatively died as a consequence of early acute respiratory failure, the main cause of death in the ICU-treated patients was unexpected cardiac arrest, probably related to overactivity of the autonomic nervous system. We conclude that to ensure a high survival rate in patients with tetanus, the treatment must be performed according to established protocol in an ICU. These studies show the results of intensive care management of 306 consecutive patients with tetanus compared with 335 patients treated conservatively in the same hospital before the institution of the ICU. The impact of the ICU treatment was manifested in a decrease in mortality, from 43.58 percent to 15 percent. In addition, while patients treated conservatively died as a consequence of early acute respiratory failure, the main cause of death in the ICU-treated patients was unexpected cardiac arrest, probably related to overactivity of the autonomic nervous system. We conclude that to ensure a high survival rate in patients with tetanus, the treatment must be performed according to established protocol in an ICU.

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