纤维蛋白原
二聚体
分泌物
化学
信使核糖核酸
基因
D-二聚体
分子生物学
生物化学
细胞生物学
生物
医学
内科学
有机化学
作者
Dre’Von A. Dobson,Richard J. Fish,Paul S. de Vries,Alanna C. Morrison,Marguerite Neerman‐Arbez,Alisa S. Wolberg
标识
DOI:10.1016/j.thromres.2024.109134
摘要
The plasma protein fibrinogen is encoded by 3 structural genes (FGA, FGB, and FGG) that are transcribed to mRNA, spliced, and translated to 3 polypeptide chains (Aα, Bβ, and γ, respectively). These chains are targeted for secretion, decorated with post-translational modifications, and assembled into a hexameric "dimer of trimers" (AαBβγ)
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