Metal-organic frameworks (MOFs) are an extraordinarily versatile class of porous materials renowned for their intricate three-dimensional skeletal architectures and exceptional chemical properties. These extraordinary attributes have pushed MOFs into the vanguard of diverse disciplines such as microporous conduction, catalysis, separation, biomedical engineering, and electrochemical sensing. The focus of this review is to offer a comprehensive summary of recent advancements in designing MOF-based electrochemical sensors for detecting organic small molecules. offer a comprehensive survey of the recent progress in the methodologies adopted for the construction of MOF composites, covering template-assisted synthesis, Modification in synthesis, and post-synthesis modification. In addition, we discuss the practical application of MOF-based electrochemical sensors in the detection of organic small molecules. Our findings highlight the superior electrochemical sensing capabilities of these novel composites compared to those of their pristine counterparts. In conclusion, we provide a condensed perspective on the potential future trajectories in this domain, underscoring the impetus for continued enquiry and enhancement of MOF composite assemblies. With sustained investigation, the horizon appears bright for electrochemical sensing of small organic molecules and their myriad applications.