医学
神经母细胞瘤
癌症研究
细胞生物学
神经科学
遗传学
生物
细胞培养
作者
Yujie Ma,Cong He,Weihong Lin,Jian Wang,Chaoliang Xu,Deshen Pan,Zuopeng Wang,Wei Yao,Rui Dong,Deshui Jia,Kai Li
标识
DOI:10.1016/j.jpedsurg.2024.08.019
摘要
Neuroblastoma (NB) originates from differentiation arrest of sympathoadrenal progenitors in the neural crest. It is necessary to reveal the differentiation mechanism of NB. Previously, we reported that Purkinje cell protein 4 (PCP4) is a well-differentiated marker of NB tissues. Herein, we explored the underlying mechanism of PCP4 induced differentiation in order to find better treatment options for patients.
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