着丝粒
PLK1
细胞生物学
Polo样激酶
动细胞
生物
细胞周期蛋白依赖激酶
细胞周期
遗传学
染色体
细胞
基因
作者
Duccio Conti,Arianna Esposito Verza,Marion E. Pesenti,Verena Cmentowski,Ingrid R. Vetter,Dongqing Pan,Andrea Musacchio
出处
期刊：Science
[American Association for the Advancement of Science]
日期：2024-09-05
卷期号：385 (6713): 1091-1097
被引量：6
标识
DOI：10.1126/science.ado5178
摘要
The centromere, a chromosome locus defined by the histone H3-like protein centromeric protein A (CENP-A), promotes assembly of the kinetochore to bind microtubules during cell division. Centromere maintenance requires CENP-A to be actively replenished by dedicated protein machinery in the early G
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