医学
内科学
心肌梗塞
经皮冠状动脉介入治疗
射血分数
逻辑回归
心脏病学
基里普班
死亡率
糖尿病
心力衰竭
内分泌学
作者
Mehmet Saygı,Ali Cevat Tanalp,Ozan Tezen,Levent Pay,Remziye Doğan,Osman Uzman,Can Yücel Karabay,İbrahi̇m Hali̇l Tanboğa,Flora Özkalaycı,Ali Karagöz
出处
期刊:Coronary Artery Disease
[Ovid Technologies (Wolters Kluwer)]
日期:2023-11-02
卷期号:35 (1): 31-37
被引量:2
标识
DOI:10.1097/mca.0000000000001285
摘要
Background The Naples prognostic score (NPS) is an effective inflammatory and nutritional scoring system widely applied as a prognostic factor in various cancers. However, the prognostic significance of NPS is unknown in ST-segment elevation myocardial infarction (STEMI). We aimed to analyze the prognostic value of the NPS in-hospital mortality in patients with STEMI. Methods The study consisted of 3828 patients diagnosed with STEMI who underwent primer percutaneous coronary intervention. As the primary outcome, in-hospital mortality was defined as all-cause deaths during hospitalization. The included patients were categorized into three groups based on NPS (group 1:NPS = 0,1,2; group 2:NPS = 3; group 3:NPS = 4) Results Increased NPS was associated with higher in-hospital mortality rates( P < 0.001). In the multivariable logistic regression analysis, the relationship between NPS and in-hospital mortality continued after adjustment for age, male sex, diabetes, hypertension, Killip score, SBP, heart rate, left ventricular ejection fraction, myocardial infarction type and postprocedural no-reflow. A strong positive association was found between in-hospital mortality and NPS by multivariable logistic regression analysis [NPS 0–1–2 as a reference, OR = 1.73 (95% CI, 1.04–2.90) for NPS 3, OR = 2.83 (95% CI, 1.76–4.54) for NPS 4]. Conclusion The present study demonstrates that the NPS could independently predict in-hospital mortality in STEMI. Prospective studies will be necessary to confirm the performance, clinical applicability and practicality of the NPS for in-hospital mortality in STEMI.
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