材料科学
纳米棒
纳米结构
拉曼光谱
拉曼散射
纳米技术
等离子体子
生物传感器
生物分子
粒子(生态学)
光电子学
光学
海洋学
物理
地质学
作者
Jae‐Myoung Kim,Jiyeon Kim,Kyungin Choi,Jwa‐Min Nam
标识
DOI:10.1002/adma.202208250
摘要
Metal nanostructures with a tunable plasmonic gap are useful for photonics, surface-enhanced spectroscopy, biosensing, and bioimaging applications. The use of these structures as chemical and biological sensing/imaging probes typically requires an ultra-precise synthesis of the targeted nanostructure in a high yield, with Raman dye-labeling and complex assay components and procedures. Here, a plasmonic nanostructure with tunable dual nanogaps, Au dual-gap nanodumbbells (AuDGNs), is designed and synthesized via the anisotropic adsorption of polyethyleneimine on Au nanorods to facilitate tip-selective Au growths on nanorod tips for forming mushroom-shaped dumbbell-head structures at both tips and results in dual gaps (intra-head and inter-head gaps) within a single particle. AuDGNs are synthesized in a high yield (>90%) while controlling the inter-head gap size, and the average surface-enhanced Raman scattering (SERS) enhancement factor (EF) value is 7.5 × 108 with a very narrow EF distribution from 1.5 × 108 to 1.5 × 109 for >90% of analyzed particles. Importantly, AuDGNs enable label-free on-particle SERS detection assays through the diffusion of target molecules into the intraparticle gap for different DNA sequences with varying ATGC combinations in a highly specific and sensitive manner without a need for Raman dyes.
科研通智能强力驱动
Strongly Powered by AbleSci AI