An artificial biocatalytic cascade for the synthesis of aryl L-threo-β-hydroxy-α-aminobutyric acids via carbon-chain extension strategy†

Chiral aryl β-hydroxy-α-aminobutyric acids (β-HABAs) and derivatives are essential building blocks for numerous active ingredients of chemicals, pharmaceuticals and bioactive natural products. Developing efficient synthesis methods to stereoselectively construct C-C...