Dehydroabietic acid protects against cerebral ischaemia–reperfusion injury by modulating microglia‐mediated neuroinflammation via targeting PKCδ

DHA specifically interacts with PKCδ, preventing its phosphorylation induced by ischaemia-reperfusion injury. These results suggest that DHA is a novel inhibitor of PKCδ and provide solid experimental foundations for using DHA in treating neuroinflammation-related conditions, such as CIRI.