医学
结直肠癌
切除术
肝切除术
内科学
放射科
肿瘤科
普通外科
外科
癌症
作者
Amber L. Simpson,Jacob Peoples,John M. Creasy,Gábor Fichtinger,Natalie Gangai,Krishna Nand Keshava Murthy,András Lassó,Jinru Shia,Michael I. D’Angelica,Richard Kinh Gian
标识
DOI:10.1038/s41597-024-02981-2
摘要
Abstract The liver is a common site for the development of metastases in colorectal cancer. Treatment selection for patients with colorectal liver metastases (CRLM) is difficult; although hepatic resection will cure a minority of CRLM patients, recurrence is common. Reliable preoperative prediction of recurrence could therefore be a valuable tool for physicians in selecting the best candidates for hepatic resection in the treatment of CRLM. It has been hypothesized that evidence for recurrence could be found via quantitative image analysis on preoperative CT imaging of the future liver remnant before resection. To investigate this hypothesis, we have collected preoperative hepatic CT scans, clinicopathologic data, and recurrence/survival data, from a large, single-institution series of patients (n = 197) who underwent hepatic resection of CRLM. For each patient, we also created segmentations of the liver, vessels, tumors, and future liver remnant. The largest of its kind, this dataset is a resource that may aid in the development of quantitative imaging biomarkers and machine learning models for the prediction of post-resection hepatic recurrence of CRLM.
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