生物
豁免特权
免疫系统
免疫学
细胞生物学
干细胞
免疫耐受
毛囊
斑秃
间质细胞
炎症
调节性T细胞
T细胞
癌症研究
白细胞介素2受体
作者
Jarish N. Cohen,Victoire Gouirand,Courtney E. Macon,Margaret M. Lowe,Ian C. Boothby,J. Moreau,Iris K. Gratz,Angelika Stoecklinger,Casey T. Weaver,Arlene H. Sharpe,Roberto R. Ricardo-González,Michael D. Rosenblum
出处
期刊:Science immunology
[American Association for the Advancement of Science]
日期:2024-01-05
卷期号:9 (91)
被引量:27
标识
DOI:10.1126/sciimmunol.adh0152
摘要
Immune tolerance is maintained in lymphoid organs (LOs). Despite the presence of complex immune cell networks in non-LOs, it is unknown whether self-tolerance is maintained in these tissues. We developed a technique to restrict genetic recombination to regulatory T cells (T
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