Development of a rapid-shaping and user-friendly membrane with long-lasting space maintenance for guided bone regeneration

A photo-crosslinkable hydrogel, composed of PEGDA, GelMA, and nanosilicate was formulated. The resulting PLGA film-PGN exhibited remarkable plasticity, maintained its shape under external forces, and fostered bone regeneration in 5 mm rat calvarial defects over a 4-week period.