高氧
氧气
氧毒性
分压
化学
毒理
统计
数学
生物
有机化学
作者
Jan Risberg,Pieter-Jan van Ooij,Lyubisa Matity
出处
期刊:Undersea & Hyperbaric Medicine
[Undersea and Hyperbaric Medical Society (UHMS)]
日期:2023-01-01
被引量:1
标识
DOI:10.22462/01.01.2023.34
摘要
A recent review suggested that the measure K = t2 x pO24.57 (t is exposure time in h, pO2 in Atm) should replace UPTD as an exposure index for pulmonary oxygen toxicity (POT) in surface-oriented diving. K would better predict reduction in vital capacity (VC) during exposure and allow prediction of recovery. Although K is more accurate estimating VC changes than UPTD, the calculation of K is more extensive, particularly when estimating hyperoxic exposure for dives with multiple pO2 segments. Furthermore, and in contrast with UPTD, K is difficult to interpret on its own given its non-linear dimension of time. We suggest that a new metric: ESOT (Equivalent Surface Oxygen Time) should be used to replace UPTD. ESOT = t x pO22.285 (t is exposure time in min, pO2 in Atm). ESOT=1 is thus the hyperoxic exposure reached after 1 min breathing of 100% O2 at surface pressure. Hyperoxic monitoring by ESOT is more practical than K to apply in an operational environment, with no loss of accuracy in POT prediction. In addition, it intuitively allows interpreting hyperoxic exposures on its own, analogous to UPTD. The daily hyperoxic threshold limits suggested by Risberg and van Ooij for two, five and an unlimited number of successive diving days would translate to ESOTs of 650, 500 and 420 respectively.
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