1Division of Gastroenterology and Hepatology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA Correspondence: Sumona Saha, MD, MS, Division of Gastroenterology and Hepatology, University of Wisconsin School of Medicine and Public Health, UW Medical Foundation Centennial Building, 1685 Highland Avenue, Madison, Wisconsin 53705-2281, USA. E-mail: [email protected] Guarantor of article: Sumona Saha, MD, MS. Specific author contributions: Sumona Saha- review of the literature, manuscript writing. Financial support: None. Potential competing interests: Dr Saha is a consultant and scientific advisor for UCB Biosciences, Inc.