Lower urinary tract dysfunction in patients with brain lesions

医学 排尿 神经科学 白质 泌尿系统 内科学 心理学 磁共振成像 放射科
作者
Ryuji Sakakibara
出处
期刊:Handbook of Clinical Neurology [Elsevier BV]
卷期号:: 269-287 被引量:79
标识
DOI:10.1016/b978-0-444-63247-0.00015-8
摘要

Stroke and brain tumor are well-known brain diseases. The incidence of lower urinary tract dysfunction (LUTD) in these patients ranges from 14% to 53%, mostly overactive bladder (OAB), and is higher when the frontal cortex is involved. This presumably reflects damage at the prefrontal cortex, cingulate cortex, and other areas that regulate (mainly inhibit) the micturition reflex. White-matter disease (WMD) is a chronic, bilateral form of cerebrovascular disease, leading to a high prevalence of OAB (up to 90%). Since WMD is particularly common in the elderly, WMD may be one of the anatomic substrates for elderly OAB. Traumatic brain injury and normal-pressure hydrocephalus are rather diffuse brain diseases, which cause OAB with a prevalence rate of 60-95%. Recent neuroimaging studies have shown a relationship between LUTD and the frontal cortex in these diseases. Data on other brain diseases, particularly affecting deep brain structures, are limited. Small infarctions, tumors, or inflammatory diseases affecting the basal ganglia, hypothalamus, and cerebellum lead to mainly OAB. In contrast, similar diseases affecting the brainstem lead to either OAB or urinary retention. The latter reflects damage at the periaqueductal gray and the pontine micturition center that directly relay and modulate the micturition reflex. Urinary incontinence (UI) in brain disease can be divided into two types: neurogenic UI (due to OAB) and functional UI (immobility and loss of initiative/cognition). These two types of UI may occur together, but management differs significantly. Management of neurogenic UI includes anticholinergic drugs that do not penetrate the blood-brain barrier easily. Management of functional UI includes behavioral therapy (timed/prompted voiding with physical assistance and bladder/pelvic floor training) and drugs to treat gait as well as cognition that facilitate continence. These treatments will maximize the quality of life in patients with brain diseases.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
ahh完成签到 ,获得积分10
刚刚
辛勤安梦完成签到,获得积分10
1秒前
Akjan完成签到,获得积分10
4秒前
查查make完成签到,获得积分10
8秒前
Jasper应助大橙子采纳,获得10
9秒前
GUO发布了新的文献求助30
10秒前
三石完成签到 ,获得积分10
10秒前
跳跃的白云完成签到 ,获得积分10
11秒前
酷酷亦寒完成签到 ,获得积分10
13秒前
量子星尘发布了新的文献求助10
15秒前
Blaseaka完成签到 ,获得积分10
16秒前
Owen应助科研通管家采纳,获得10
16秒前
深情安青应助科研通管家采纳,获得10
16秒前
16秒前
汉堡包应助科研通管家采纳,获得10
17秒前
小二郎应助科研通管家采纳,获得30
17秒前
爆米花应助科研通管家采纳,获得10
17秒前
沉静的浩然完成签到,获得积分10
18秒前
开朗的绮山完成签到,获得积分10
18秒前
18秒前
老迟到的土豆完成签到 ,获得积分10
21秒前
单薄的日记本完成签到,获得积分10
21秒前
大橙子发布了新的文献求助10
22秒前
舒适的天奇完成签到 ,获得积分10
23秒前
24秒前
26秒前
都是小儿卡通书完成签到,获得积分10
27秒前
28秒前
陶醉的又夏完成签到 ,获得积分10
28秒前
lily完成签到 ,获得积分10
31秒前
32秒前
子苓完成签到 ,获得积分10
34秒前
Jun完成签到 ,获得积分10
34秒前
phil完成签到,获得积分10
35秒前
祁乐安发布了新的文献求助20
35秒前
如初完成签到,获得积分10
36秒前
zzuwxj完成签到,获得积分10
39秒前
糊涂的语兰完成签到,获得积分10
43秒前
多余完成签到,获得积分10
44秒前
喝酸奶不舔盖完成签到 ,获得积分10
44秒前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Handbook of Industrial Diamonds.Vol2 1100
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038157
求助须知:如何正确求助?哪些是违规求助? 3575869
关于积分的说明 11373842
捐赠科研通 3305650
什么是DOI,文献DOI怎么找? 1819255
邀请新用户注册赠送积分活动 892655
科研通“疑难数据库(出版商)”最低求助积分说明 815022