Early and long-term changes in adjacent vertebral body bone mineral density determined by quantitative computed tomography after posterolateral fusion with transpedicular screw fixation

医学 骨矿物 定量计算机断层扫描 核医学 椎骨 椎体 腰椎 脊柱融合术 固定(群体遗传学) 腰椎 骨密度 外科 骨质疏松症 泌尿科 内科学 人口 环境卫生
作者
Ali Balcı,Orhan Kalemcı,Fatih Kaya,Göktuğ Akyoldaş,Kemal Yücesoy,Dinç Özaksoy
出处
期刊:Clinical Neurology and Neurosurgery [Elsevier]
卷期号:145: 84-88 被引量:12
标识
DOI:10.1016/j.clineuro.2016.04.014
摘要

The aim of this study is to investigate vertebral body bone mineral density (BMD) changes following posterolateral fusion with transpedicular screw fixation using quantitative computerized tomography (QCT) in short and relatively long-term periods.A retrospective study was performed to investigate vertebral body BMD changes in the patients who underwent posterolateral fusion with transpedicular screw fixation at thoracic and lumbar spine. A total of 160 patients were enrolled into the study. According to the follow-up period, patients were divided into two subgroups (group 1, early follow-up, mean follow-up period, 279.3±162.3 days and group 2, later follow-up, mean follow-up period, 969.1±274.2 days). The trabecular BMDs (mg/cm³) were measured from T12 to L5 as screw free levels by using QCT measurement software. Comparisons between preoperative and postoperative BMD values were assessed using paired t-test.The mean postoperative BMD values of both group 1 and 2 weresignificantly lower, compared with the preoperative values (79.2±31.3mg/cm³ vs. 91.5±31.4mg/cm(3), 76.1±25.5mg/cm(3) vs. 89.3±30.4mg/cm(3), p<0.001 and p<0.001, respectively). There was no significant correlation between BMD loss and number of fused segments. Vertebral BMD loss was significantly higher in the L3 vertebra when located caudally to the operation site than when located cranially (-27.7±19.8% vs. -12.8±27.1%; p<0.01).The vertebral body BMD values are decreased at the adjacent of the posterolateral fusion with transpedicular screw fixation levels in both cephalad and caudad sides at an average of 9-months-follow-up postoperatively. This BMD loss persisted, but not worsened at an average of 32-months-follow-up. Vertebral BMD loss was significantly higher in the L3 vertebra when located caudally versus cranially to the surgery site.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
852应助张益达采纳,获得10
1秒前
1秒前
2秒前
冷静映安发布了新的文献求助10
2秒前
小二郎应助cat采纳,获得10
2秒前
icaohao完成签到,获得积分10
3秒前
成就的笑南完成签到 ,获得积分10
3秒前
myf完成签到 ,获得积分10
3秒前
liaohuui完成签到,获得积分20
3秒前
乐观寻绿完成签到 ,获得积分10
3秒前
情怀应助张焚采纳,获得10
3秒前
harvey1989发布了新的文献求助10
4秒前
平常梦岚完成签到 ,获得积分10
4秒前
笨笨行云发布了新的文献求助30
4秒前
当当完成签到,获得积分10
5秒前
5秒前
SUE发布了新的文献求助10
6秒前
alex发布了新的文献求助10
6秒前
6秒前
Jozee完成签到,获得积分10
6秒前
7秒前
春锅锅完成签到,获得积分10
8秒前
喜悦的月光完成签到,获得积分10
8秒前
8秒前
科研通AI2S应助hh0采纳,获得10
9秒前
9秒前
CipherSage应助谷粱靖柔采纳,获得30
10秒前
10秒前
思源应助Yeah采纳,获得10
11秒前
11秒前
高兴微笑完成签到,获得积分10
11秒前
1234645678发布了新的文献求助10
11秒前
11秒前
12秒前
12秒前
全球发布了新的文献求助10
12秒前
科研通AI2S应助hhh采纳,获得10
13秒前
科研通AI2S应助咸鱼一号采纳,获得10
13秒前
打打应助xzy998采纳,获得10
14秒前
14秒前
高分求助中
The late Devonian Standard Conodont Zonation 2000
The Lali Section: An Excellent Reference Section for Upper - Devonian in South China 1500
Nickel superalloy market size, share, growth, trends, and forecast 2023-2030 1000
Smart but Scattered: The Revolutionary Executive Skills Approach to Helping Kids Reach Their Potential (第二版) 1000
Mantiden: Faszinierende Lauerjäger Faszinierende Lauerjäger 800
PraxisRatgeber: Mantiden: Faszinierende Lauerjäger 800
A new species of Coccus (Homoptera: Coccoidea) from Malawi 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3245464
求助须知:如何正确求助?哪些是违规求助? 2889085
关于积分的说明 8256869
捐赠科研通 2557437
什么是DOI,文献DOI怎么找? 1386114
科研通“疑难数据库(出版商)”最低求助积分说明 650285
邀请新用户注册赠送积分活动 626541