天然产物
催交
工作流程
基石
自然(考古学)
分离(微生物学)
步伐
计算机科学
产品(数学)
生化工程
数据科学
计算生物学
纳米技术
工程类
化学
生物信息学
生物
系统工程
地理
考古
材料科学
几何学
古生物学
数据库
立体化学
数学
大地测量学
作者
Alexander E. Fox Ramos,Laurent Evanno,Erwan Poupon,Pierre Champy,Mehdi A. Beniddir
摘要
Covering: up to 2019Landmark advances in bioinformatics tools have recently enhanced the field of natural products research, putting today's natural product chemists in the enviable position of being able to perform the efficient targeting/discovery of previously undescribed molecules by expediting the prioritization of the isolation workflow. Among these advances, MS/MS molecular networking has appeared as a promising approach to dereplicate complex natural product mixtures, leading to a real revolution in the "art of natural product isolation" by accelerating the pace of research of this field. This review illustrates through selected cornerstone studies the new thinking in natural product isolation by drawing a parallel between the different underlying philosophies behind the use of molecular networking in targeting natural products.
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