异尾类下目
细胞凋亡
结直肠癌
细胞培养
化学
A549电池
肺癌
活力测定
癌症
传统医学
癌症研究
生物
医学
生物化学
肿瘤科
植物
内科学
遗传学
作者
Pei Si Xia,Le Yan Li,Yong Kang Li,Fang Chen,Zhong Qiu Liu,Jin Wu,Peng Wu
标识
DOI:10.1016/j.phytol.2022.05.006
摘要
Three new compounds were isolated from Artemisia anomala, and their structures were determined using HR-ESI-MS, IR, UV, and NMR. The antitumor activities of the three compounds were evaluated in the human lung cancer cell line A549 and the human colorectal cancer cell line HCT116. The results showed that compound 2 significantly inhibited cell viability and proliferation and promoted apoptosis of HCT116 and A549 cells, suggesting that compound 2 may be used for colon and lung cancer treatments in clinical practice.
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