Correlation of Preoperative Serum and Intraoperative Peritoneal Lavage Fluid Ca-125 Levels with Postoperative Tumor Histology in Patients with Endometrial Cancer: A Prospective-Controlled Study

医学 腹膜液 子宫内膜癌 淋巴结 癌症 前瞻性队列研究 阶段(地层学) 卵巢癌 泌尿科 胃肠病学 内科学 古生物学 生物
作者
Suleyman Gunhan Doluoglu,Mehmet Ali Karaca,Onur Erol
出处
期刊:Journal of Investigative Surgery [Taylor & Francis]
卷期号:35 (6): 1248-1252 被引量:1
标识
DOI:10.1080/08941939.2021.2024307
摘要

The role of Ca-125 in endometrial cancer is not fully known. Some authors have reported high Ca-125 levels in patients with recurrent or advanced endometrial cancer, whereas others have stated that Ca-125 levels and the advance of the disease were not correlated in endometrial cancer. This makes it inevitable for clinicians to search for different measurement methods or interpretation of the present tumor markers. The aim of this study was to evaluate the relationship between Ca-125 values of the serum and abdominal lavage fluid and postoperative histopathological parameters in patients with endometrial carcinoma.The study included patients who were diagnosed with endometrial cancer in the Gynecology Clinic and were planned to undergo surgery. The correlations of clinicopathological parameters with preoperative values of Ca-125 measured from serum and abdominal lavage fluid were investigated. The Spearman correlation test was applied in the analysis of correlations of serum and abdominal lavage fluid Ca-125 values with postoperative tumor characteristics.The serum Ca-125 values were determined to be positively correlated with surgical stage, tumor diameter, and lymph node involvement (p = 0.03; p = 0.04; and p = 0.01, respectively). No correlation was determined between tumor grade and serum Ca-125 level. The level of Ca-125 in the abdominal lavage fluid was observed to be correlated with surgical stage and tumor grade, but not with tumor diameter or lymph node involvement (p = 0.01, p = 0.04, respectively).The value of Ca-125 in the abdominal lavage fluid has a positive correlation with the surgical stage and tumor grade in patients with endometrial carcinoma.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
3秒前
忒寒碜完成签到,获得积分10
10秒前
14秒前
XU博士完成签到,获得积分10
16秒前
哭泣青烟完成签到 ,获得积分10
17秒前
roundtree完成签到 ,获得积分0
21秒前
等待谷南完成签到,获得积分10
24秒前
Alan完成签到 ,获得积分10
27秒前
xdc完成签到,获得积分10
29秒前
量子星尘发布了新的文献求助10
30秒前
依依完成签到 ,获得积分0
39秒前
MISSIW完成签到,获得积分10
40秒前
HHHAN发布了新的文献求助10
43秒前
胡胡完成签到 ,获得积分10
44秒前
火星上小土豆完成签到 ,获得积分10
54秒前
杰尼龟的鱼完成签到 ,获得积分10
58秒前
安然完成签到 ,获得积分10
59秒前
张希伦完成签到 ,获得积分10
59秒前
任性翠安完成签到 ,获得积分10
1分钟前
dong完成签到 ,获得积分10
1分钟前
神说完成签到,获得积分0
1分钟前
量子星尘发布了新的文献求助10
1分钟前
Aimee完成签到 ,获得积分10
1分钟前
徐彬荣完成签到,获得积分10
1分钟前
研友_8yN60L完成签到,获得积分10
1分钟前
搜集达人应助科研通管家采纳,获得10
1分钟前
光亮的自行车完成签到 ,获得积分10
1分钟前
李东东完成签到 ,获得积分10
1分钟前
王多肉完成签到,获得积分10
1分钟前
Iiiilr完成签到 ,获得积分10
1分钟前
杨幂完成签到,获得积分10
1分钟前
1分钟前
hellokitty完成签到,获得积分10
1分钟前
1分钟前
小四发布了新的文献求助10
1分钟前
1分钟前
西瓜完成签到 ,获得积分10
1分钟前
包容的忆灵完成签到 ,获得积分10
1分钟前
高兴尔冬发布了新的文献求助10
1分钟前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Handbook of Industrial Diamonds.Vol2 1100
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038039
求助须知:如何正确求助?哪些是违规求助? 3575756
关于积分的说明 11373782
捐赠科研通 3305574
什么是DOI,文献DOI怎么找? 1819239
邀请新用户注册赠送积分活动 892655
科研通“疑难数据库(出版商)”最低求助积分说明 815022