Effect of Ultrasound on One-Pot Conversion of Alcohols to Nitro and Azido Compounds

Synthesis of aliphatic nitro and azido compounds from corresponding alcohols under ultrasonic irradiation was studied. Ultrasonic irradiation of the reaction mixture ROH/NaNO2/HCl allowed to shorten the reaction time and increase yields of aliphatic nitro compounds. Ultrasonic irradiation of the reaction mixture PhCH2OH/NaN3/PPh3 resulted in formation of PhCH2N3 in yields comparable with those of the silent experiments. The next product was benzyl chloride and not benzylamine as was described in the literature.