Spherical Agglomerates of m-Aminobenzoic Acid: Solvent Selection, Preparation, Mechanism, and Characterization

结块 范德瓦尔斯力 结晶 乙二醇 化学 溶剂 氢键 化学工程 过饱和度 结晶学 材料科学 有机化学 分子 工程类
作者
Yiting Xiao,Liping Wang,Zhenguang Tuo,Yufeng Gao,Pei Zhao,Ailing Liu,Ying Bao
出处
期刊:Industrial & Engineering Chemistry Research [American Chemical Society]
卷期号:60 (22): 8280-8290 被引量:10
标识
DOI:10.1021/acs.iecr.1c01031
摘要

Solvents for spherical agglomerates preparation are usually selected according to the Lifshitz–van der Waals acid–base theory with negative adhesion free energies. However, some solvents with positive adhesion free energies in which spherical agglomerates can be obtained are easily ignored. This work proposes that solvents should be screened comprehensively by theoretical calculation combined with experiments using m-aminobenzoic acid (m-ABA) as a model compound. According to the Lifshitz–van der Waals acid–base theory, water, isopropyl alcohol, and ethylene glycol with negative adhesion free energies were screened out as the possible solvents for the preparation of m-ABA spherical agglomerates. Crystallization experiments showed that in addition to the three solvents, methanol and ethanol with positive adhesion free energies were also appropriate for spherical crystallization of m-ABA. A common feature of the five solvents which can form spherical agglomerates is that they have both hydrogen-bond-donating and hydrogen-bond-accepting capabilities. The single-factor analysis method was used to systematically investigate the effects of stirring speed, terminal temperature, and supersaturation on spherical agglomerates of m-ABA. The formation mechanism of m-ABA spherical agglomerates was elucidated with the help of the in situ Pixact Crystallization Monitoring system. Comparative experiments proved that the obtained spherical agglomerates exhibit better chemical stabilities and crystal form stability than needle-like crystals.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
刘寄奴发布了新的文献求助10
1秒前
su发布了新的文献求助10
3秒前
深情安青应助胡航航采纳,获得10
4秒前
小小发布了新的文献求助30
5秒前
CodeCraft应助苗条梦玉采纳,获得10
6秒前
jia完成签到 ,获得积分10
7秒前
10秒前
10秒前
11秒前
Ava应助坚定路人采纳,获得10
13秒前
15秒前
16秒前
潘善若发布了新的文献求助10
16秒前
戴岱发布了新的文献求助10
18秒前
19秒前
20秒前
momo发布了新的文献求助10
22秒前
大模型应助潘善若采纳,获得10
22秒前
23秒前
jolt发布了新的文献求助10
24秒前
25秒前
传奇3应助戴岱采纳,获得10
26秒前
nini完成签到,获得积分10
28秒前
zzzjh发布了新的文献求助10
28秒前
量子星尘发布了新的文献求助10
29秒前
29秒前
31秒前
32秒前
nini发布了新的文献求助10
35秒前
Lucas应助XAN采纳,获得10
36秒前
潘善若发布了新的文献求助10
36秒前
棠棠完成签到 ,获得积分10
36秒前
39秒前
yyer完成签到,获得积分10
39秒前
41秒前
FashionBoy应助潘善若采纳,获得10
42秒前
慕青应助忐忑的阑香采纳,获得10
42秒前
momo发布了新的文献求助10
43秒前
冰淇淋完成签到,获得积分10
43秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3989297
求助须知:如何正确求助?哪些是违规求助? 3531418
关于积分的说明 11253893
捐赠科研通 3270097
什么是DOI,文献DOI怎么找? 1804884
邀请新用户注册赠送积分活动 882087
科研通“疑难数据库(出版商)”最低求助积分说明 809158