医学
前列腺癌
肿瘤科
前列腺
癌症研究
阉割
内科学
癌症
激素
作者
Oliver Sartor,Johann S. de Bono,Kim N.,Karim Fizazi,Ken Herrmann,Kambiz Rahbar,Scott T. Tagawa,Luke T. Nordquist,Neil Vaishampayan,Ghassan El‐Haddad,Chandler H. Park,Tomasz M. Beer,Alison Armour,Wendy J. Pérez-Contreras,Michelle DeSilvio,Euloge Kpamegan,Germo Gericke,Richard A. Messmann,Michael J. Morris,Bernd J. Krause
标识
DOI：10.1056/nejmoa2107322
摘要
Metastatic castration-resistant prostate cancer remains fatal despite recent advances. Prostate-specific membrane antigen (PSMA) is highly expressed in metastatic castration-resistant prostate cancer. Lutetium-177 (177Lu)–PSMA-617 is a radioligand therapy that delivers beta-particle radiation to PSMA-expressing cells and the surrounding microenvironment.
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