医学
脑膜中动脉
栓塞
队列
改良兰金量表
倾向得分匹配
外科
回顾性队列研究
血肿
慢性硬膜下血肿
内科学
缺血
缺血性中风
作者
Alejandro Enríquez-Marulanda,Santiago Gomez-Paz,Mohamed M. Salem,Akashleena Mallick,Rouzbeh Motiei-Langroudi,Jeffrey E. Arle,Martina Stippler,Efstathios Papavassiliou,Ron L. Alterman,Christopher S. Ogilvy,Justin M. Moore,Ajith J. Thomas
出处
期刊:Neurosurgery
[Oxford University Press]
日期:2021-05-06
卷期号:89 (3): 486-495
被引量:40
标识
DOI:10.1093/neuros/nyab192
摘要
Middle meningeal artery (MMA) embolization is an emerging minimally invasive endovascular technique for chronic subdural hematoma (cSDH). Currently, limited literature exists on its safety and efficacy compared with conventional treatment (open-surgical-evacuation-only).To compare MMA embolization to conventional treatment.Retrospective analysis of patients with cSDHs treated with MMA embolization in a single center from 2018 to 2019 was performed. Comparisons were made with a historical conventional treatment cohort from 2006 to 2016. Propensity score matching analysis was used to assemble a balanced group of subjects.A total of 357 conventionally treated cSDH and 45 with MMA embolization were included. After balancing with propensity score matching, a total of 25 pairs of cSDH were analyzed. Comparing the embolization with the conventional treatment group yielded no significant differences in complications (4% vs 4%; P > .99), clinical improvement (82.6% vs 83.3%; P = .95), cSDH recurrence (4.3% vs 21.7%; P = .08), overall re-intervention rates (12% vs 24%; P = .26), modified Rankin scale >2 on last follow-up (17.4% vs 32%; P = .24), as well as mortality (0% vs 12%; P = .09). Radiographic improvement at last follow-up was significantly higher in the open surgery cohort (73.9% vs 95.6%; P = .04). However, there was a trend for lengthier last follow-up for the historical cohort (72 vs 104 d; P = .07).There was a trend for lower recurrence and mortality rates in the embolization era cohort. There were significantly higher radiological improvement rates on last follow-up in the surgical only cohort era. There were no significant differences in complications and clinical improvement.
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