内科学
动脉硬化
甘油三酯
内分泌学
医学
胆固醇
糖尿病
2型糖尿病
高密度脂蛋白
脂蛋白
低密度脂蛋白
胃肠病学
出处
期刊:Labmedicine
[Oxford University Press]
日期:2009-01-01
被引量:2
摘要
Objective To compare the application value of the atherogenic index of plasma (AIP),low-density lipoprotein cholesterol(LDL-C) / high-density lipoprotein cholesterol (HDL-C),arterial stiffness index(AI) and lipoprotein combine index (LCI) in patients with type 2 diabetes mellitus (DM). Methods The levels of triglyceride (TG),total cholesterol(TC) and HDL-C in 124 rype 2 DM patients and 111 healthy controls were determined and LDL-C,LDL-C/HDL-C,AIP,AI and LCI were calculated. Then the type 2 DM patients were classified into two groups: HDL-C0.91 mmol/L group and HDL-C≥0.91 mmol/L group. Results The AIP,AI and LCI in type 2 DM patients were higher than those in healthy controls(P 0.001). Among these indexes,AIP was the most sensite,and the next in order was AI. AI,LDL-C/HDL-C and especially AIP in HDL-C0.91 mmol/L group were higher than that in HDL-C≥0.91 mmol/L group(P0.01). The AIP in blood lipid rising group had significant difference between before and after the treatment(P0.001). Conclusions Comparatively AIP is better than other arteriosclerosis indexes. AIP is the most valuable index for determining artherosclerosis and reflecting its risk in type 2 DM patients.
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