The effect of total sleep deprivation under workload on spontaneous brain activity in medical staff: a resting-state functional MR imaging study

The current study aims to assess the effect of total sleep deprivation (TSD) under workload on spontaneous brain activity in medical staff and to further investigate its latent associations with clinical markers. It was concluded that spontaneous brain activity abnormalities occurred during TSD under workload, which might explain the reduced performance of these participants on neurocognitive tests.