药物输送
靶向给药
合理设计
放射治疗
癌症治疗
靶向治疗
医学
纳米技术
癌症研究
癌症
材料科学
内科学
作者
Lin Ding,Minli Liang,Chenchen Li,Xinting Ji,Junfeng Zhang,Wei‐Fen Xie,Rui L. Reis,Furong Li,Shuo Gu,Yanli Wang
标识
DOI:10.1002/smtd.202200853
摘要
Abstract Conventional chemotherapy and radiotherapy are nonselective and nonspecific for cell killing, causing serious side effects and threatening the lives of patients. It is of great significance to develop more accurate tumor‐targeting therapeutic strategies. Nanotechnology is in a leading position to provide new treatment options for cancer, and it has great potential for selective targeted therapy and controlled drug release. 2D nanomaterials (2D NMs) have broad application prospects in the field of tumor‐targeted delivery systems due to their special structure‐based functions and excellent optical, electrical, and thermal properties. This review emphasizes the design strategies of tumor‐targeted delivery systems based on 2D NMs from three aspects: passive targeting, active targeting, and tumor‐microenvironment targeting, in order to promote the rational application of 2D NMs in clinical practice.
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