癌症研究
肺癌
转录组
突变体
生物
细胞
肿瘤异质性
癌症
医学
病理
基因表达
基因
遗传学
作者
Songji Oh,Jaemoon Koh,Tae Min Kim,Soyeon Kim,Jeonghwan Youk,Miso Kim,Bhumsuk Keam,Yoon Kyung Jeon,Ja‐Lok Ku,Dong‐Wan Kim,Doo Hyun Chung,Dae Seog Heo
标识
DOI:10.1158/1078-0432.ccr-24-0160
摘要
Histologic transformation from EGFR-mutant non-small cell lung cancer (NSCLC) to small-cell lung cancer (SCLC) is a key mechanism of resistance to EGFR tyrosine kinase inhibitors (TKI). However, transcriptomic changes between NSCLC and transformed SCLC (t-SCLC) remain unexplored.
科研通智能强力驱动
Strongly Powered by AbleSci AI