Palladium-Catalyzed Multicomponent [4+2] Cycloaddtion of 1, 4-Enynes with CO and Arylamines to Access Polycyclic γ-Lactams via Dearomative Rearrangement

Herein we report a novel palladium-catalyzed intermolecular dearomative [4+2] cycloaddition of 1, 4-enynes with CO and arylamines. Compared with the well-known Himbert intramolecular arene/allene cycloaddtion, this method provides a facile...