医学
Modic变化
单变量分析
Oswestry残疾指数
小关节切除术
经皮
外科
腰椎
椎间盘切除术
回顾性队列研究
背痛
腰椎间盘疾病
腰痛
多元分析
内科学
椎板切除术
脊髓
替代医学
病理
精神科
作者
Lei Li,Chao Wang,Hao Zhang,Zhiming Liu,Zheng Lian,Han Li,Hao Tao,Xuexiao Ma
摘要
ABSTRACT Objectives Lumbar disc herniation (LDH) is a common degenerative spinal disease in clinical practice. This study aims to investigate the impact of Modic changes (MCs) on postoperative recovery and disease recurrence following percutaneous endoscopic lumbar disc discectomy (PELD), providing important insights for improving the management of chronic low back pain. This study investigates the 1‐year progression rate of MCs after PELD and their impact on surgical outcomes and recurrence. Methods This retrospective cohort study analyzed data from 419 patients with single‐segment lumbar disc herniation who underwent PELD between January 2019 and December 2022. Lumbar MRI assessed preoperative and postoperative MCs. Pain levels and surgical outcomes were evaluated using the visual analog scale, Oswestry Disability Index, and Macnab criteria. Univariate analysis explored the relationship between postoperative MCs and pain, while subgroups investigated the associations between postoperative efficacy, recurrence, and MCs type and area. Results One‐year follow‐up revealed that the probability of MCs postsurgery was 24.8%. Patients with postoperative MCs had significantly lower pain scores compared with the control group ( p < 0.05). Univariate analysis indicated that the type and area of postoperative MCs were risk factors for poor outcomes in PELD patients ( p < 0.05). During the 1‐year follow‐up, recurrence rates in the no‐MCs and MCs groups were 3.8% and 9.6%, respectively ( p < 0.05). Univariate analysis concluded that the area of postoperative MCs was a risk factor for PELD recurrence. Conclusion The postoperative MCs, as a risk factor, may have a detrimental effect on the surgical efficacy and short‐term recurrence of LDH following PELD based on a large sample. Furthermore, the harmful effect is affected by the area and type of the postoperative MCs.
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