Towards sustainable omega-3 fatty acids production – A comprehensive review on extraction methods, oxidative stability and bio-availability enhancement

• Limitations and sustainability setbacks of PUFA extracted from fish oil were detailed. • Potential microalgal biomass were studied and explored as a source of alternatePUFA. • Novel techniques for extraction and factors governing optimum PUFA synthesis from microbial derivatives were reviewed. • The present challenges and futuristic prospects in microbial.