电化学发光
纳米技术
计算机科学
生物传感器
生化工程
材料科学
化学
工程类
色谱法
检出限
作者
Yajuan Yan,Lurong Ding,Jialian Ding,Ping Zhou,Bin Su
标识
DOI:10.1002/cbic.202400389
摘要
Electrochemiluminescence (ECL) is one of the most powerful techniques that meet the needs of analysis and detection in a variety of scenarios, because of its highly analytical sensitivity and excellent spatiotemporal controllability. ECL combined with microscopy (ECLM) offers a promising approach for quantifying and mapping a wide range of analytes. To date, ECLM has been widely used to image biological entities and processes, such as cells, subcellular structures, proteins and membrane transport properties. In this review, we first introduced the mechanisms of several classic ECL systems, then highlighted the progress of visual biosensing and bioimaging by ECLM in the last decade. Finally, the characteristics of ECLM were summarized, as well as some of the current challenges. The future research interests and potential directions for the application of ECLM were also outlooked.
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