核糖核酸
N6-甲基腺苷
化学
生物
生物化学
甲基化
基因
甲基转移酶
作者
Subiding Tayier,Enlin Tian,Guifang Jia
标识
DOI:10.1002/ijch.202400029
摘要
Abstract N 6 ‐methyladenosine (m 6 A), as the most abundant and well‐studied RNA modification, can be reversibly added or removed by m 6 A methyltransferase and demethylase. The further molecular and biological function of m 6 A is achieved by the recognition of its binding protein. m 6 A functions in the diverse progress of RNA processing, including transcription regulation, splicing, nuclear export, stability, and translation, to regulate the fate of cells. Although been extensively studied in various animal cell systems, research on m 6 A's regulatory functions in plant cells lags. In recent years, with a deepening understanding of the functions of m 6 A and the development of various sequencing technologies, researches on m 6 A in plant cells have gradually increased. In this review, we focused on discussing the molecular functions of m 6 A in the nucleus and cytoplasm, aiming to elucidate the specific molecular mechanisms by which m 6 A regulates the fate of RNAs in plants. Finally, we provide some perspectives on future investigations of the detailed molecular mechanism of m 6 A‐mediated regulation in plants, which might provide insights into future strategies for achieving multiple growth regulatory processes in crops.
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