色谱法
加速溶剂萃取
萃取(化学)
定量分析(化学)
线性判别分析
定性分析
化学
计算机科学
人工智能
社会科学
社会学
定性研究
作者
Fangyuan Gao,Haiyan Chen,Yusha Luo,Ji‐Kuai Chen,Yan Ling,Jian Zhu,Guorong Fan,Tingting Zhou
标识
DOI:10.1016/j.fochx.2021.100162
摘要
Angelica dahurica is a famous functional food and herb. To guarantee quality of A. dahurica, a strategy "Q-markers targeted screening" was successfully developed by sufficient extraction of compounds and the targeted screening of qualitative and quantitative markers calculated through chemometric methods based fingerprints. Accelerated solvent extraction was selected due to its prominent advantages exhibiting the maximum extraction yields and varieties of compounds and especially excellent reproducibility (RSD < 1). After extraction, the fingerprints of A. dahuricae samples were established. For the preliminary herb authenticity, the targeted screening of 23 quantitative markers were performed by similarity analysis and hierarchical cluster analysis based on the fingerprints, which were identified by liquid chromatography tandem mass spectrometry (LC-MS). Subsequently, for further quality control, the targeted screening of nine quantitative markers were done by similarity analysis & linear discriminant analysis, which were determined by LC. Lastly, the strategy was successfully applied to quality assessment of A. dahurica samples.
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