CD19
CD20
抗原
B细胞
CD22
癌症研究
医学
免疫学
生物
抗体
作者
Dina Schneider,Ying Xiong,Darong Wu,Peirong Hu,Leah Alabanza,Brittany L. Steimle,Hasan Mahmud,Kim Anthony-Gonda,Winfried Krueger,Zhongyu Zhu,Dimiter S. Dimitrov,Rimas J. Orentas,Boro Dropulić
出处
期刊:Science Translational Medicine
[American Association for the Advancement of Science (AAAS)]
日期:2021-03-24
卷期号:13 (586)
被引量:93
标识
DOI:10.1126/scitranslmed.abc6401
摘要
Trispecific duoCAR-T cells with optimized costimulatory domains effectively kill tumor cells in antigen-heterogeneous and antigen-replete tumor models.
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