What is the Impact of Cinnamon Supplementation on Blood Pressure? A Systematic Review and Meta-Analysis

荟萃分析 科学网 医学 科克伦合作 传统医学 内科学 血压 斯科普斯 科克伦图书馆 合并分析 随机对照试验 系统回顾 梅德林 生物 生物化学
作者
Abed Ghavami,Hossein Khadem Haghighian,Neda Roshanravan,Rahele Ziaei,Ehsan Ghaedi,Amir Reza Moravejolahkami,Gholamreza Askari
出处
期刊:Endocrine, metabolic & immune disorders [Bentham Science Publishers]
卷期号:21 (5): 956-965 被引量:6
标识
DOI:10.2174/1871530320666200729143614
摘要

Background and Aims: This study was designed to make a systematic review and meta-analysis on randomized controlled trials (RCTs) assessing the effect of cinnamon on blood pressure (BP). Methods: A systematic computerized literature search of PubMed, Scopus, Web of Science, Cochrane Library and Google Scholar databases were conducted up to August 2019. All RCTs using cinnamon supplements in adults were included in this systematic review and meta-analysis. Results: Out of 927 records, 8 trials that enrolled 582 participants were included. The pooled effect size showed that SBP did not change following cinnamon supplementation. (WMD: -0.61mmHg; 95% CI: -1.36, 0.14, P= 0.111). Also cinnamon supplementation in long-duration (≥ 8weeks) had a significant effect on SBP (WMD: -1.25 mmHg; 95% CI: -2.22, -0.28, P= 0.012). Pooled analysis showed that cinnamon had a significant effect on DBP (WMD: -0.93mmHg, 95% CI: -1.55 to -0.32, P= 0.003). In addition, results from both duration subsets and high dose (>1500 mg/day) of cinnamon supplementation were significant. Conclusion: Our findings revealed that cinnamon supplementation has favorable effects on DBP although results about SBP were not the same. Nonetheless, further studies are required.
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