Three arachidonic acid metabolic pathways Involved in inflammation

Inflammation occurs in various diseases.It can deteriorate the process of disease and cause with serious output.The main sources of inflammation mediators are the products of arachidonic acid metabolism.Various products of play ara chidonic acid metabolism different roles during inflammation.The review focuses on the recent update about three key metabolic products of arachidonic acid metabolism(such as PGE2、LTXs and EETs)and their contribution in inflammation initiation,and the interaction of these three pathways. Key words: Inflammation; Arachidonic acid metabolism; Key product