原发性醛固酮增多症
医学
继发性高血压
主动脉夹层
弹性蛋白
心脏病学
风险因素
醛固酮增多症
解剖(医学)
醛固酮
内科学
血压
外科
主动脉
病理
作者
Tartière Jm,L Kesri,Jean-Jacques Mourad,Michel E. Safar,Jacques Blacher
出处
期刊:PubMed
日期:2003-10-01
卷期号:28 (4): 185-9
被引量:4
摘要
Aortic dissection is a rare but severe disease. Numerous risk factors have been reported, all leading to an alteration of arterial structures, particularly extracellular matrix. Aortic dissection is a complication of arterial hypertension, whatever its origin. Primary aldosteronism, frequent cause of secondary arterial hypertension, is associated with arterial structural alterations, indirectly by a pressure factor, and directly by aldosterone, which modifies collagen contents and elastin/collagen ratios. In addition to the three previously reported cases, the three cases reported in the present paper lead to the hypothesis of a causal relationship between aldosteronism and aortic dissection. The need for hypertension screening and diagnosis of its potential causes, namely primary aldosteronism, is highlighted.
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