Molecular Biology: Principles and Practice

PART I: FOUNDATIONS Studying the Molecules of Life DNA: The Repository of Biological Information Chemical Basis of Information Molecules Protein Structure Protein Function PART II: NUCLEIC ACID STRUCTURE & METHODS DNA and RNA Structure Studying Genes Genomes, Transcriptomes, and Proteomes Topology: Functional Deformations of DNA Nucleosomes, Chromatin, and Chromosome Structure PART III: INFORMATION TRANSFER DNA Replication DNA Mutation and Repair Moment of Discovery Homologous Recombination Site-Specific Recombination and Transposition DNA-Dependent Synthesis of RNA RNA Processing The Genetic Code Protein Synthesis PART IV: REGULATION Regulating the Flow of Information The Regulation of Gene Expression in Bacteria Transcriptional Regulation of Gene Expression in Eukaryotes Post-Transcriptional Regulation of Gene Expression in Eukaryotes Gene Regulation in Development Online Appendix: Model Organisms