The association between orthostatic blood pressure changes and arterial stiffness

动脉硬化 医学 脉冲波速 直立生命体征 血压 心脏病学 内科学 糖尿病 内分泌学
作者
Pingping Wu,Guoyan Xu,Min Pan,Lin Li,Wenqin Cai
出处
期刊:Blood Pressure Monitoring [Lippincott Williams & Wilkins]
卷期号:27 (4): 239-246 被引量:6
标识
DOI:10.1097/mbp.0000000000000594
摘要

Although orthostatic hypotension (OH) and orthostatic hypertension (OHT) can independently predict cardiovascular events, the underlying mechanisms remain controversial. Our study aimed to examine the relationships between orthostatic blood pressure (BP) changes and arterial stiffness.In this cross-sectional analysis, 1820 participants were divided into three groups according to BP changes within 3 min of orthostatism: the OH group had a decrease of >20 mmHg in SBP or >10 mmHg in DBP, the OHT group had an increase of ≥20 mmHg in SBP, and the orthostatic normotensive (ONT) group had normal changes. Arterial stiffness was assessed by measuring the carotid-femoral pulse wave velocity (cfPWV).OH and OHT were observed in 257 (14.1%) and 62 (3.4%) participants, respectively. Subjects in the OH group were significantly older, were more likely to have hypertension and diabetes, and had higher cfPWV than those in the ONT group ( P < 0.05); however, no differences were found between the ONT and OHT groups. Stepwise multiple regression analysis of the subgroups stratified by hypertension and diabetes revealed that age was related to increased cfPWV in all stratifications, and the change in SBP was significantly positively correlated with cfPWV in hypertensive subjects; however, this association was not observed in nonhypertensive subjects.We found that arterial stiffness was closely related to OH but not to OHT. In addition to expanding current knowledge of the relationship between orthostatic BP changes and arterial stiffness, our study underlines the importance of age, SBP changes, and hypertension in evaluating arterial stiffness.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
YYT发布了新的文献求助10
刚刚
1秒前
嘘嘘完成签到,获得积分20
1秒前
勤奋柚子完成签到,获得积分10
1秒前
1秒前
我是老大应助lee采纳,获得10
1秒前
郭一一发布了新的文献求助10
1秒前
文献无碍发布了新的文献求助10
1秒前
1秒前
张张张xxx发布了新的文献求助10
1秒前
2秒前
852应助yyyq0721采纳,获得10
2秒前
yaya发布了新的文献求助10
2秒前
2秒前
YU完成签到 ,获得积分10
2秒前
生信精准科研完成签到,获得积分10
3秒前
3秒前
烟花应助开心的城采纳,获得10
3秒前
lz完成签到,获得积分20
4秒前
4秒前
有话好好硕完成签到 ,获得积分10
4秒前
4秒前
不想开学吧完成签到 ,获得积分10
5秒前
smottom应助ZH采纳,获得10
5秒前
Serenity完成签到,获得积分10
6秒前
benben055发布了新的文献求助20
6秒前
情怀应助干净怀寒采纳,获得10
6秒前
斯文败类应助含蓄丸子采纳,获得10
7秒前
小樊同学发布了新的文献求助10
7秒前
7秒前
菜菜完成签到,获得积分10
7秒前
COCO完成签到,获得积分10
8秒前
kyrie发布了新的文献求助10
8秒前
8秒前
9秒前
jacob258发布了新的文献求助50
9秒前
Katherine完成签到,获得积分10
9秒前
情怀应助hui采纳,获得10
10秒前
10秒前
Ryan发布了新的文献求助10
10秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Cognitive Neuroscience: The Biology of the Mind 1000
Technical Brochure TB 814: LPIT applications in HV gas insulated switchgear 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Picture Books with Same-sex Parented Families: Unintentional Censorship 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3969335
求助须知:如何正确求助?哪些是违规求助? 3514162
关于积分的说明 11172430
捐赠科研通 3249456
什么是DOI,文献DOI怎么找? 1794853
邀请新用户注册赠送积分活动 875437
科研通“疑难数据库(出版商)”最低求助积分说明 804809