Abstract This chapter provides an overview of noncovalent interactions in the field of supramolecular chemistry. The use of noncovalent forces to form supramolecular structures is documented. Supramolecular interactions can be both directional and nondirectional and can enable chemists to develop discrete assemblies and networks of molecules and/or ions with prescribed properties and functions. Concepts of host‐guest chemistry, molecular recognition, and self‐assembly emerge from an understanding of how supramolecular interactions control assembly processes. Examples that highlight the utility of employing supramolecular interactions to form functional structures and materials are given.