作者
Lingbin Du,Huizhang Li,Youqing Wang,Chen Zhu,Rongshou Zheng,Siwei Zhang,Wanqing Chen,Jié He
摘要
Objective: To estimate the incidence and mortality of colorectal cancer (CRC) in China, providing basic information of treatment and prevention in CRC. Methods: In 2016, National Central Cancer Registry (NCCR) collected registration data in 2013 from local cancer registries and assessed the data according to the auditing methods and evaluation criteria formulated by NCCR. 347 cancer registries submitted data of 2013 to NCCR. Qualified data from 255 registries was pooled, analyzed and stratified by area (urban/rural), gender, and age. CRC incidence and mortality were estimated using national population in 2013. Results: In 2013, the estimate of new cases diagnosed with CRC in China was 347.9 thousands, with 9.45% of new cancer cases. The crude incidence of CRC was 25.57/100, 000 (28.64/100, 000 for male and 22.34/100, 000 for female, 30.92/100, 000 in urban areas and 19.35/100, 000 in rural areas), ranking fourth in all cancer. The age-standardized rates by China population and by world population were 17.45/100, 000 and 17.20/100, 000, respectively. Cumulative incidence of CRC in China was 2.05%. The estimated CRC deaths of China was 164, 900 in 2013, accounting for 7.39% of overall cancer deaths. The crude mortality rate for CRC was 12.11/100, 000 (13.49/100, 000 for male and 10.67/100, 000 for female, 14.41/100, 000 in urban and 9.45/100, 000 in rural), ranking fifth in all cancer. The age-standardized rates by China population and by World population for mortality were 7.87/100, 000 and 7.76/100, 000, respectively. Cumulative mortality rate of CRC in China was 0.82%. For both of incidence and mortality, males had much higher rates than females, while urban areas had much higher rates than rural areas. The incidence and mortality rates of CRC increased greatly with age, especially after 35 or 40 years old, and reached the peak in the age group of 80 or 85+ year old. Conclusion: The disease burden of CRC was still serious in China. Primary prevention and early detection of CRC in China is crucial.目的: 了解2013年中国结直肠癌的发病与死亡情况,为结直肠癌的防治提供基础信息。 方法: 提取2016年全国肿瘤登记中心收集的2013年中国肿瘤登记地区的肿瘤登记资料,按照全国肿瘤登记中心制订的审核方法和评价标准对347个肿瘤登记地区的数据进行评估,其中255个登记地区的数据符合入选标准。按地区(城乡)、性别、年龄别,结合2013年全国人口数据,估计2013年全国结直肠癌的发病与死亡情况。 结果: 全国2013年新发结直肠癌病例数约为34.79万例,占全部恶性肿瘤发病的9.45%,位居恶性肿瘤发病的第4位。全国结直肠癌粗发病率为25.57/10万,其中男性为28.64/10万,女性为22.34/10万,中国人口标化发病率(中标率)为17.45/10万,世界人口标化发病率(世标率)为17.20/10万,累积发病率为2.05%。城市地区发病率为30.92/10万,农村地区发病率为19.35/10万。2013年全国结直肠癌死亡病例数约为16.49万例,占全部恶性肿瘤死亡的7.39%,位居恶性肿瘤死亡的第5位。结直肠癌粗死亡率为12.11/10万,其中男性为13.49/10万,女性为10.67/10万,中标死亡率为7.87/10万,世标死亡率为7.76/10万,累积死亡率为0.82%。城市地区死亡率为14.41/10万,农村地区死亡率为9.45/10万。结直肠癌的发病率和死亡率均为男性高于女性,城市高于农村,年龄别发病率和死亡率以35岁或40岁之后快速增长,至80岁或85岁以上达到高峰。 结论: 中国结直肠癌的疾病负担仍然较重,结直肠癌的早期发现和尽早预防至关重要。.