膜
磁导率
膜透性
化学
生物物理学
生物化学
生物
作者
Julia Thomas,Mark S. Friddin,Oscar Ces,Yuval Elani
摘要
We report a bottom-up synthetic biology approach to engineering vesicles with programmable permeabilities. Exploiting the concentration-dependent relationship between constitutively active pores (alpha-hemolysin) and blockers allows blockers to behave as molecular regulators for tuning permeability, enabling us to systematically modulate cargo release kinetics without changing the lipid fabric of the system.
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